cortexmap
v1.0.5
Published
CLI for lesion unfolding on mouse cerebral cortex.
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CortexMap
The localization of traumatic brain injury (TBI) lesions directly correlates with motor disabilities and cognitive impairment. By unfolding magnetic resonance (MR) images of a lesioned rat cortex on a two-dimensional (2D) cytoarchitecture map of the cortex, it is possible to predict the severity of the resulting cognitive and behavioral impairment.
CortexMap is a web application to estimate the location of the lesion on mouse cerebral cortex caused by TBI induced by lateral fluid-percussion injury. The application unfolds user-determined TBI lesion measurements, e.g., from histologic sections to a reference template, and estimates the total lesion area, including the percentage of cortex damaged in different cytoarchitectural cortical regions.